A Stronger Immune System*

Clinical Research Area #2

In a world filled with health threats, your body’s ability to respond to and fight immune stressors is critical. But when it comes to supporting the immune system, the bioactive compounds in Thrive Adaptogenics supplements are showing real results.*

In a human study, twelve healthy adults drank 330 ml (10 fl. oz.) Thrive Adaptogenics Original for 8 weeks. A measurement of blood taken before and after the test showed a 32% increase IL-2 levels which stimulate the adaptive immune system and a 30% increase in the natural killer cells that form the immune system’s first line of defense.¹

In an additional series of tests involving cells of the immune system, the results demonstrated that noni induces production of chemical messengers that activate parts of the immune system in mice.^2-3

More and more studies—in-vivo and in-vitro alike—are showing similar results. Thrive Adaptogenics supplements support and enhance the immune system.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

References:
1. Ma D, Jun Z, Jianhua G, et al. (2008). The effect of Tahitian Noni Juice on antioxidation and immune function. Chinese Med. Res. Clin. 6(6): 8-10.
2. Hirazumi, A and Furusawa, E. An immunomodulatory polysaccharide-rich substance from the fruit juice of Morinda citrifolia (noni) with antitumour activity. 1999. Phytotherapy Research 13:380-387.
3. Furusawa, et al. Antitumour Potential of a Polysaccharide-rich Substance from the Fruit Juice of Morinda citrifolia (Noni) on Sarcoma 180 Ascites Tumour in Mice. Phytother. Res., 2003. 17:1158-1164.
4. Hirazumi, A. et al. Anticancer Activity of Morinda citrifolia (Noni) on Intraperitoneally Implanted Lewis Lung Carcinoma in Syngeneic Mice. Proc. West. Pharmacol. Soc., 1994. 37:145-146.
5. Wong, D.K.W. Are Immune Responses Pivotal to Cancer Patient's Long Term Survival? Two Clinical Case-study Reports on the Effects of Morinda citrifolia (Noni). Hawaii Med. J., 2004. 63:182-184.
6. Liu. et al. Two novel glycosides from the fruits of Morinda citrifolia (noni) inhibit AP-1 transactivation and cell transformation in the mouse epidermal JB6 cell line. Cancer Research 2001. 61:5749–5756.
7. Hirazumi, A. et al. Immunomodulation contributes to the anticancer activity of Morinda citrifolia (noni) fruit juice. 1996. Proc. West. Pharmacol. Soc. 39:7-9.
8. Arpornsuwan, T. and Punjanon, T. Tumor Cell-Selective Antiproliferative Effect of the Extract from Morinda citrifolia Fruits. Phytother. Res., 2006. 20:515-517.
9. Xu, J, et al. Tahitian Noni™ Equine Essentials™ Regulates LPS-Induced COX-2 and Cytokine Expression in Equine Neonatal Monocytes: A Preliminary Study. 2006. 3rd European Workshop on Equine Nutrition. Campobosso, Italy.
10. Schäfer, M. et al. Enhanced Bactericidal Activity against Escherichia coli in Calves Fed Morinda citrifolia (Noni) Puree. J Vet Intern Med 2008; 22:499–502.
11. Palu et al. (2008). The effects of Morinda citrifolia L. (noni) on the immune system: Its molecular mechanisms of action. J. Ethnopharmacol. 115: 502–506.